The Workshop program is availble in .pdf format here.


State-of-the-art- Speakers

Francesco Blasi, M.D., Dr. Med. H.C.    
Urokinase, Receptor, Inhibitors: But this is Very Old Now!

BlasiDr. Blasi received his M.D. (1961) from the University of Naples, Naples, Italy, after which he decided to pursue a doctorate degree in biological research at the Max Planck Institute of Biophysics in Frankfurt. Germany. At the Max Planck Institute, Dr. Blasi studied the effect of radiation on the activity of proteins, and in 1964 he returned to the University of Naples where he worked as a Professor of Genetics until 1980. From 1968 to 1970, Dr. Blasi was a visiting scientist at the National Institute of Arthritis and Metabolic Diseases at the NIH, Bethesda, Maryland, USA, in the laboratory of Nobel Prize laureate, Christian Anfinsen. This training helped Dr. Blasi establish a bacterial genetics section at the University of Naples to study how genes are regulated. From then on, Dr. Blasi's research diversified to study tumor metastasis that led him to discover and characterize urokinase-type plasminogen activator (uPA), its membrane receptor (uPAR), and it's role in cancer. After spending six years as a Professor of Molecular Biology at University of Copenhagen, Denmark, Dr. Blasi directed research at the San Raffaele Hospital in Milan, Italy. There he became involved in creating the FIRC Institute of Molecular Oncology Foundation (IFOM) in Milan, a research institute of excellence. Since 2011 he has been serving as the Deputy Director for Science at IFOM, where he pursues his passion studying transcriptional regulation of oncogenic factors. Dr. Blasi's distinguished career has been filled with several awards and honors, notably, membership in the European Molecular Biology Organization (E.M.B.O.), Dr. Honoris Causae (1993) from the University of Copenhagen, and the International Society of Fibrinolysis and Thrombolysis (ISFT) prize in 1994. Dr. Blasi has published over 250 research papers in prestigious scientific journals.


Nicola J. Mutch, Ph.D.
Platelets are Key Modulators of Fibrinolysis

mutchDr. Mutch received her Ph.D. from the University of Aberdeen, UK in 2000 after which she completed two postdoctoral fellowships at the University of Aberdeen (2001-2003) and the University of Illinois at Urbana-Champaign (2007-2010). She then became an independent research fellow in cardiovascular medicine at the University of Leeds, UK (2007-2010) and is currently a British Heart Foundation Fellow and Senior Lecturer, at the University of Aberdeen. She was a recipient of the D. Collen Young Investigator Award, ISFP, Brighton (2012) and is currently a member of the Council for the International Society of Fibrinolysis and Proteolysis (Class of 2018) and the British Society of Haemostasis and Thrombosis. Dr Mutch has been an invited speaker at a number of International meetings and has published her work on platelets, fibrinolysis, and thrombosis in a number of peer-reviewed journals. She has also authored a number of book chapters in this field.


Dr. Manuel Yepes, M.D.
Tissue-type Plasminogen Activator is a Master Regulator of Synaptic Function in the Brain

YepesDr. Yepes received his M.D. from Javeriana University, Santafe de Bogota, Colombia, in 1989 after which he trained and became a board certified Neurologist from Georgetown University, Washington, D.C in 1998. That same year. Dr. Yepes was appointed as the director of the Stroke Center and Ultrasound Laboratory, Georgetown University Medical Center, Washington, D.C. His enthusiasm and fascination for research led him to take up a four-year postdoctoral position in the laboratory of Dr. Daniel Lawrence at the American Red Cross/George Washington University, USA. In 2004, Dr. Yepes joined Emory University, Atlanta, Georgia, USA, where he is currently Professor of Neurology and a member of the Center for Neurodegenerative Disease. Dr, Yepes also serves as the director of the Stroke Center in the VA Medical Center (VAMC) in Atlanta, USA. His active duties as a clinician involve taking care of ischemic stroke patients in Emory University Hospital and the VAMC. As a member of the Center for Neurodegenerative Disease at Emory University, Dr. Yepes directs research on cereberovascular neuroscience studying the molecular mechanisms of pathways regulating neuronal apoptosis and survival in the ischemic brain. Dr. Yepes is on the editorial board of several prestigious journals that include, Journal of Thrombosis and Haemostasis, and Journal of Trauma and Treatment. Through the course of his career, Dr. Yepes has been bestowed with several honors, such as, the Hugh H. Hussey Award for Excellence in Medical student Teaching (1997) and the Roland H. Lange Fellowship (2003) for excellence in research in Biomedical Sciences. Dr. Yepes has also been active in organizing the XXII Congress of the International Society of Thrombosis and Haemostasis (ISTH) (2009), and was elected as Vice-chair of the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis (2014). Dr. Yepes has published in many prestigious journals, and has co-authored chapters on basic and clinical sciences.


Shaun Lee, Ph.D.
Blood Ties: Host Microbe Interactions in Group A Streptococcal Pathogenesis

LeeDr. Lee received his Ph.D. in molecular microbiology from the Oregon Health Sciences University, Portland, Oregon (2003) where he also completed a one year postdoctoral fellowship before transferring to Jack Dixon's laboratory in the Department of Pharmacology at the University of California, San Diego, School of Medicine (2004-2009). During his postdoctoral fellowship in Dr. Dixon's laboratory he was a recipient of a NCI Oncogenesis and Growth Regulation fellowship. Dr. Lee is currently an Associate Professor in the Department of Biological Sciences, University of Notre Dame, Notre Dame, IN. He is also a member of the Eck Institute for Global Health, the Notre Dame Center for Rare and Neglected diseases and an adjunct faculty member of the W. M. Keck Center for Transgene Research. He is currently a recipient of a NIH Innovator Award for studies on the design and use of a class of bacterial toxins known as bacteriocins. Dr. Lee's primary research goal is to elucidate mechanisms associated with the biosynthesis and utilization of this and other bacterial toxins and bacterial virulence facts.